| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | Riverside "A" | Aubree Lundin, Alexandra Bengard, Sadie Reeves, Zoe Enge | 2:00.38 | 4 splits50: 30.08 (30.08) 100: 1:03.51 (33.43) 150: 1:32.70 (29.19) 200: 2:00.38 (27.68) |
| 2 | Spartanburg "A" | Claire Lauer, Kathryn Freeman, Ellie Fisher, Katelyn Nunez | 2:04.37 | 4 splits50: 31.78 (31.78) 100: 1:07.21 (35.43) 150: 1:37.82 (30.61) 200: 2:04.37 (26.55) |
| 3 | Spartanburg "B" | Harriet Lynch, Charlie Kimsey, Eliza Martin, Amelia Phillips | 2:13.11 | 4 splits50: 33.03 (33.03) 100: 1:10.97 (37.94) 150: 1:43.93 (32.96) 200: 2:13.11 (29.18) |
| 4 | Riverside "B" | Hadley North, Katharine Ceneviva, Alana Moore, Reese Eaker | 2:17.53 | 4 splits50: 33.76 (33.76) 100: 1:12.97 (39.21) 150: 1:44.85 (31.88) 200: 2:17.53 (32.68) |
| 5 | Riverside "C" | Olivia Mehagan, Lauren Hughes, Anna Ceneviva, Callie Garner | 2:20.13 | 4 splits50: 35.85 (35.85) 100: 1:16.52 (40.67) 150: 1:47.78 (31.26) 200: 2:20.13 (32.35) |
| 6 | Spartanburg "C" | Colleen Gallagher, Mallori McCoy, Anna Vidrine, Kennedy Bozard | 2:20.88 | 4 splits50: 34.05 (34.05) 100: 1:14.54 (40.49) 150: 1:52.15 (37.61) 200: 2:20.88 (28.73) |
| 7 | Spartanburg "D" | Sofia Rubio, Elaina Martin, Emma Greene, Seher Islam | 2:34.98 | 4 splits50: 38.61 (38.61) 100: 1:24.17 (45.56) 150: 2:01.66 (37.49) 200: 2:34.98 (33.32) |