| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | Hilton Head Island "A" | Vivian Shave, Piper Lucas, Cadence Smith, Olivia Johnson | 2:00.65 | |
| 2 | Beaufort "A" | AMORETTE CHAPMAN, MICHALLE RICKS, ELIZABETH JONES, LYDIA FRANCE | 2:15.23 | |
| 3 | May River "A" | Christina Gluck, Kaila Joyce, Janelle Trett, Evie Clayton | 2:15.37 | |
| 4 | Heritage Academy "A" | Maia Balarezo, Ella Olivetti, Ariana Balarezo, Olivia Fish | 3:02.93 |