| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | LEXINGTON "A" | Reagan Taylor, Angelina Luo, Riley Halloran, Lyla Jones | 2:12.81 | |
| 2 | River Bluff "A" | Keelyn Davis, Ellie Wells, Caroline Wells, Ellie Starr | 2:12.99 | |
| 3 | River Bluff "B" | Lena Rankin, Maddison Honour, Jasmine Silva Velasco, Cara Hodges | 2:38.40 | |
| 4 | River Bluff "C" | Elana Jahnke, Caroline Cully, Maelle Wong, Sydney Beeler | 2:43.78 | |
| 5 | LEXINGTON "B" | Aubriana Keller, Jaclyn Liebenrood, Iva Francis, Arlie Eubanks | 2:45.91 | |
| NS | LEXINGTON "C" | — |