Sep 13, 2025
| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | St James "A" | Sydney Fennell, Jenna Guthinger, Zlata Kulikovska, Ciena Farrell | 1:59.52 | |
| 2 | Socastee "A" | McKinen Solheim, Kyleigh Malena, Anisten Satterfield, Samantha Riley | 2:02.26 | |
| 3 | Carolina Forest "A" | Carly Silva, Gabriella Suarez, Kayleigh Hubbard, Macie Mosley, Hailey Scaturro, Dominique Ulmer | 2:08.78 | |
| 4 | Socastee "B" | Madison Ellerbe, Madison Malena, Olivia Capuzzi, Peyton Groff | 2:11.81 | |
| 5 | North Myrtle Beach "A" | Kaitlyn Jones, Sydney Carroll, Robyn Walsh, Skyleigh Averitt | 2:12.23 | |
| 6 | Myrtle Beach "A" | Danna Contreras, Adelae Flint, Ansley Link, Stella Gutovitz, Sofia Contreras | 2:16.33 | |
| 7 | North Myrtle Beach "B" | Christiana Baeli, Sadie Olson, Sadie Averitt, Lainee Smith | 2:16.95 | |
| 8 | Carolina Forest "B" | Kendall Hubbard, Lillie Herlevi, Margaret Aycock, Maricely Sanchez Perez | 2:24.75 | |
| 9 | Socastee "C" | Isabella Bottaro, Breanna Thompson, Kaitlyn Mandel, Ava Midkiff | 2:26.33 | |
| 10 | Waccamaw "A" | Lillian Kunes, Georgia Madigan, Grace Ratliffe, Ellington Steel | 2:26.82 | |
| 11 | Christian Academy Myrtle Beach "A" | Amelia Walden, Elliot Burnette, Quinn Taylor, Nora Thompson | 2:32.52 | |
| 12 | Aynor "A" | Kensley Staples, McKay Beaver, Teagan Gierstorf, Brylee Wirt | 2:48.24 |