WKHS vs IHS vs AHS vs BCHS vs FCHS
| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | Irmo "A" | RAWSON BRABHAM, Savannah Forrest, Molly Nix, Addison Courtney | 2:39.40 | |
| 2 | Brookland-Cayce "A" | Eve Bryan, Heather Long, Zoe Bryan, Sarah Stikeleather | 2:57.37 | |
| 3 | White Knoll "B" | MacKenzie Goff, Reece Blevins, Savannah Campbell, Josie Featherstone | 4:26.26 | |
| DQ | White Knoll "A" | Isabella Steele, Hailee Gunter, Lilliana Tinajero, Isabel Blevins | — | |
| DQ | Airport "A" | — |