| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| Daniel "A" | Julianna Tang, Elizabeth Russell, Bailey Choi, Mary Greene | 2:02.56 | ||
| Daniel "B" | Piper Finneran, Jocelyn Campbell, Eva Harding, Sophie Ayers | 2:12.70 | ||
| Powdersville "A" | Adiya Kapcoe, Brooke Wilder, Cara Tollison, Aliyah Butler | 2:13.50 | ||
| Easley "A" | Molly Sanders, Madelyn McKever, Heidi McKever, Eliza Cornell | 2:14.78 | ||
| Wren "A" | Samantha Riddle, Emily Baird, Brooklyn Osbourne | 2:23.69 | ||
| Powdersville "B" | Everlee Lugo, Paige Ulrey, Aubrey Dill, Madelyn Atkinson | 2:29.10 | ||
| Travelers Rest "B" | Kali Anderson, Aleena Dixon, Ava Garrett, Riley Stokes | 2:43.91 |