| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| Brashier Middle College "A" | Gabriella Chesney, Geneva Lyle, Reid Chandgie, Addison Chesney | 2:19.72 | ||
| Greenville Tech Charter "A" | Zoey Zimmerman, Piper Schreel, Gracyn Schreel, Ruby Archibald | 2:28.71 | ||
| Powdersville "A" | Brooke Wilder, Cara Tollison, Aliyah Butler | 2:31.00 | ||
| Greenville Hurricanes "A" | Brinlee Williams, Hattie Brown, Sadie Davis, Hannah Watson | 2:33.10 | ||
| Brashier Middle College "B" | Audrey Ratliff, Madelyn Baltz, Addison Bayer, Hope Sequeira | 2:51.72 | ||
| Greenville Hurricanes "B" | Teagin Costanzo, Lucy Osborn, Adelyn Gustek, Elisa Pettett | 2:55.72 | ||
| Powdersville "B" | Adiya Kapcoe, Paige Ulrey, Everlee Lugo | 2:56.26 |