| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | West Ashley "A" | Sofia Savic, Ashlyn Cook, Soleil Smith, Lila Perlmutter | 2:19.94 | |
| 2 | West Ashley "B" | Caroline Brown, Gabriela Ross, Tallulah Branton, Isabella Luciano | 2:33.63 | |
| 3 | West Ashley "C" | Gabriella Parks, Julia Hodges, Kaylee Berry, Lillian Parks | 2:42.31 | |
| 4 | West Ashley "D" | Alexandra Doose, Ella Lathan, Ana Savic, Emma Griggs | 3:03.88 |