| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | Dutch Fork "A" | Olivia Newman-Norlund, Keli Taylor, Stella Kichukov, Isabella Eyler | 2:27.20 | |
| 2 | Dutch Fork "B" | Brianna Neel, Evelyn Hickman, Jade Bakos, Julia Jacobs | 2:51.69 | |
| 3 | American Leadership "A" | Eleanor Beers, Charlotte Bell, Elissa DeGroff, Maria Nava | 3:07.14 | |
| DQ | Mid-Carolina "A" | Miriam Eshaak, Baylee Willetts, Tailee Followell, Hannah Kubacz | — |