| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | Aiken "A" | Elsa Horcher, Macy Harper, Greta Olson, Gabrielle Blaszczak | 2:02.95 | |
| 2 | Aiken "B" | Gina Hofstetter, Gabrielle RIchardson, Sarah Richardson, Adalin Grigsby | 2:22.19 | |
| 3 | South Aiken "A" | Briella O'Quinn, Addison Moss, Marian Mason, Kalila O'Quinn | 2:22.25 | |
| 4 | South Aiken "B" | Sarah Tamburello, Katherine Dalbec, Linda Colquitt, Olivia Ascherman | 2:26.80 | |
| 5 | South Aiken "C" | Cheyanne Knott, Lexie Whitman, Sophia Bice, Trinity Farkas | 3:07.04 |