| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | Blythewood "A" | Lily Kang, Abigail Christian, Addison Maradei, Catherine Maradei | 2:02.97 | |
| 2 | Blythewood "B" | Saskia Hankwitz, Ava Sanders, Nora Kang, Anya Hutchinson | 2:15.15 | |
| 3 | LEXINGTON "B" | Iva Francis, Charlotte Spencer, Aubriana Keller, Sarah Kolb | 2:25.81 | |
| 4 | Blythewood "C" | Reilly Lewis, Emily Pickens, Sophia Gammons, Gracie Thames | 2:26.75 | |
| 5 | Mid-Carolina "A" | Tailee Followell, Baylee Willetts, Olivia Haskett, Hannah Kubacz | 2:48.10 | |
| DQ | LEXINGTON "A" | Reagan Taylor, Angelina Luo, Riley Halloran, Lyla Jones | — | |
| DQ | LEXINGTON "C" | Miruna Savu, Olivia Sagot, Kyleigh Sturkie, Celeste Greenidge | — |