| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | Spartanburg "A" | Harriet Lynch, Kathryn Freeman, Clarissa Vereen, Ellie Fisher | 2:07.04 | 4 splits50: 32.75 (32.75) 100: 1:07.92 (35.17) 150: 1:38.26 (30.34) 200: 2:07.04 (28.78) |
| 2 | Spartanburg Day "A" | Mary Gilman, Madeleine Belmont, Essence Olley, Meredith Garrett | 2:14.30 | 4 splits50: 33.80 (33.80) 100: 1:12.15 (38.35) 150: 1:41.88 (29.73) 200: 2:14.30 (32.42) |
| 3 | Spartanburg "B" | Colleen Gallagher, Amelia Phillips, Eliza Martin, Olivia Smith | 2:16.31 | 4 splits50: 34.37 (34.37) 100: 1:12.71 (38.34) 150: 1:45.78 (33.07) 200: 2:16.31 (30.53) |
| 4 | Boiling Springs "A" | Bevin Hardy, Cerys Ewing, Alexa Boykin, Kaylin Archabald | 2:26.49 | 4 splits50: 37.53 (37.53) 100: 1:10.12 (32.59) 150: 1:41.98 (31.86) 200: 2:26.49 (44.51) |
| 5 | Spartanburg "C" | Faye Krick-Aigner, Elaina Martin, Charlie Kimsey, Kennedy Bozard | 2:29.86 | 4 splits50: 40.40 (40.40) 100: 1:25.19 (44.79) 150: 2:01.52 (36.33) 200: 2:29.86 (28.34) |
| 6 | Spartanburg "D" | Olivia Battocchio, Charlotte Smith, Emma Greene, Seher Islam | 2:30.34 | 4 splits50: 40.92 (40.92) 100: 1:21.07 (40.15) 150: 1:57.61 (36.54) 200: 2:30.34 (32.73) |