| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | Clover "A" | Leah Pirrello, Natalie Heinle, Emma Dent, Isabella Ward | 2:00.42 | 4 splits50: 31.10 (31.10) 100: 1:04.97 (33.87) 150: 1:32.35 (27.38) 200: 2:00.42 (28.07) |
| 2 | Rock Hill "A" | Katherine Sandu, Lydia Ghent, Sophia McCall, Maggie Compton | 2:07.24 | 4 splits50: 34.82 (34.82) 100: 1:07.78 (32.96) 150: 1:39.12 (31.34) 200: 2:07.24 (28.12) |
| 3 | York Comprehensive "A" | Mollie Hanks, Ava Haese, Adelynn Branch, Caroline Mitchell | 2:07.46 | 4 splits50: 36.27 (36.27) 100: 1:06.97 (30.70) 150: 1:37.77 (30.80) 200: 2:07.46 (29.69) |
| 4 | Clover "B" | Alana Spraul, Annie Hasty, Lily Larkin, Elaina Hodnett | 2:15.96 | 4 splits50: 35.00 (35.00) 100: 1:09.66 (34.66) 150: 1:45.96 (36.30) 200: 2:15.96 (30.00) |
| 5 | Rock Hill "B" | Riley Elston, Julianna Haas, Collins McFadden, Samantha Garcia | 2:26.54 | 4 splits50: 36.44 (36.44) 100: 1:20.36 (43.92) 150: 1:55.34 (34.98) 200: 2:26.54 (31.20) |
| 6 | Clover "C" | Nadalie Hoppe, Ashley Cook, Abbigail Perkins, Alexia Rottmann | 2:30.64 | 4 splits50: 39.40 (39.40) 100: 1:22.40 (43.00) 150: 1:58.46 (36.06) 200: 2:30.64 (32.18) |
| 7 | Rock Hill "C" | Campbell Compton, Parker Crenshaw, Kennedy Query, Leah Simon | 2:38.02 | 4 splits50: 38.40 (38.40) 100: 1:22.44 (44.04) 150: 2:02.58 (40.14) 200: 2:38.02 (35.44) |