| Place | Team | Swimmers | Time | Splits |
|---|---|---|---|---|
| 1 | Indian Land "A" | Sophie Cline, Sophie Walker, Olivia Thorpe, Aspyn Walker | 2:04.67 | 4 splits50: 37.70 (37.70) 100: 1:05.64 (27.94) 150: 1:35.49 (29.85) 200: 2:04.67 (29.18) |
| 2 | Northwestern "A" | Kyleigh McCoy, Brooke Schake, Hannah Andrychowski, Charlie Wallace | 2:08.63 | 4 splits50: 36.12 (36.12) 100: 1:10.29 (34.17) 150: 1:41.06 (30.77) 200: 2:08.63 (27.57) |
| 3 | Indian Land "B" | Cilena Williams, Abigail Solomon, Isabella D'Alessandro, Hanna Baker | 2:26.17 | 4 splits50: 42.09 (42.09) 100: 1:21.01 (38.92) 150: 1:54.45 (33.44) 200: 2:26.17 (31.72) |
| 4 | Northwestern "B" | Eva Moore, Eliana Dugger, Alexandria Taylor, Rawley Biddix | 2:28.96 | 4 splits50: 38.43 (38.43) 100: 1:22.30 (43.87) 150: 1:57.23 (34.93) 200: 2:28.96 (31.73) |
| 5 | South Pointe "A" | Avery Totherow, Grace Robinson, Ava Easley, Caile Dawson | 2:52.17 | 4 splits50: 37.85 (37.85) 100: 1:32.22 (54.37) 150: 2:12.17 (39.95) 200: 2:52.17 (40.00) |
| 6 | Indian Land "C" | Luciana Palacios, Paula Palacios, Cassidy Sullivan, Gwendolyn Fleck | 3:01.72 | 4 splits50: 55.88 (55.88) 100: 1:36.83 (40.95) 150: 2:32.33 (55.50) 200: 3:01.72 (29.39) |